Premature ejaculation (PE) is a distressing male sexual dysfunction that can be present from the first sexual encounter or can develop later in life, where a man ejaculates too quickly during sexual intercourse. It is a common ejaculation problem.

Men with premature ejaculation appear to go through the same process of ejaculation as other men, but it happens more quickly and with a reduced feeling of control. A combination of physiological and psychological factors is believed to impact on ejaculatory latency.

Research suggests that serotonin plays a central role which medicines can help with.